Diagnosing autoimmune hepatitis in paediatric patients – we still haven’t found what we are looking for

autoimmune hepatitis in iran: what we know, what we don’t know and requirements for better management

Comparing Theories: What are We Looking For?

Two recent papers, (Harless and Camerer, 1994) and (Hey and Orme, 1994) were both addressed to the same question: which is the 'best' theory of decision making under risk? The two papers shared a common concern: the appropriate trade-o between the descriptive accuracy of a theory and the predictive parsimony of that theory. In other respects, however, the two papers di ered markedly: rst in the...

Autoimmune Hepatitis in Iran: What We Know, What We Don’t Know and Requirements for Better Management

DOI: 10.5812/hepatmon.840 Copyright c 2012 Kowsar M.P.Co. All rights reserved. Implication for health policy/practice/research/medical education: Autoimmune hepatitis is a quite serious disease, and will get worse if not treated properly. AIH is a disease that needs to be managed under the supervision of a team of specialists, including at least one hepatologist or a gastroenterologist with an ...

Surrogate end points of quality of life assessment: have we really found what we are looking for?

Outcome research is a new interesting field in medical research. Some years ago, a document of the American Society of Clinical Oncology distinguished the outcomes of a treatment into patient-outcomes (overall survival and quality of life) and cancer-outcomes (response rate), giving higher priority to patient outcomes. This document is one of the best structured instruments to evaluate and clas...

Lymphangioleiomyomatosis: what do we know and what are we looking for?

Lymphangioleiomyomatosis (LAM) is a rare disease characterised by proliferation of abnormal smooth muscle-like cells (LAM cells) leading to progressive cystic destruction of the lung, lymphatic abnormalities and abdominal tumours. It affects predominantly females and can occur sporadically or in patients with tuberous sclerosis complex. This review describes the recent progress in our understan...